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|您的位置>>大会特别演讲>>大会演讲>>Immunopathological Insights of Ocular biopsies[转载] 发送给好友  发表评论,已评论0次   阅读:1950次 关键词:免疫

 
   [作者]: maojin [单位或文章来源]: Chi-Chao Chan, M.D. Immunopathology Section, Laboratory of Immunology, National Eye Institute, National Institutes of Health, USA [加入时间]:2002/8/24 [稿件录用方式]: 书面交流
  Immunopathological Insights of Ocular biopsies   
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In difficult or refractory cases, the ideal management of intraocular inflammation and malignancy may require a tissue diagnosis. Diagnostic vitrectomy is one well-established method for acquiring such tissue; however, in some patients, the diagnostic pathology is limited to the choroids and retina, making vitrectomy alone insufficient. In such cases, full-thickness retinal and/or choroidal biopsies of the involved tissues may be useful. Such ocular biopsies may be analyzed by routine and molecular pathology, immunohistochemistry, immunology and microbiology. Prompt handling and adequately processing specimens is invaluable in increasing the yield of these procedures. The utility of ocular biopsy in diagnosis of ocular inflammatory, infectious and malignant diseases are illustrated and summarized in several classical reported cases. With careful consideration of clinical manifestations, ocular biopsies and tissue sampling will help to improve and confirm clinical diagnosis, understanding of disease pathogenesis, and guide appropriate therapy.



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