目的 通过收集整理首都医科大学附属北京同仁医院眼病理室自1961年12月至2002年6月共273例病理诊断为泪腺上皮性肿瘤的石蜡切片标本及临床相关资料，进行回顾性总结分析，明确泪腺上皮性肿瘤的病理类型及特征，进一步为临床诊治工作提供更科学的参考指标。方法 将所有病理诊断为泪腺多形性腺瘤、多形性腺癌、泪腺囊腺癌、腺癌等泪腺上皮性肿瘤的273例石蜡切片标本，共计261例患者的病理学及临床相关资料进行收集整理。病理学特征包括肿瘤大小、形状、颜色、取材所见、光学显微镜下所见和病理类型，临床资料包括年龄、性别、病史、眼别、影像学表现、查体所见、术中所见、手术后治疗和随访，将病理检查和临床资料总结纳，明确泪腺上皮性肿瘤中不同类型的病理学表现，了解其发病年龄、病程进展、复发情况等指标，及其与临床诊断、治疗和预后的关系。结果 泪腺上皮性肿瘤中各种类型所占比例由高向低排列依次为多形性腺瘤、泪腺囊腺癌、多形性腺癌、泪腺腺癌和其它。在所有病例中，术后复发一次以上者有12例，其复发率为4.6％。 结论 泪腺上皮性肿瘤中以良性混合瘤最为多见。泪腺上皮性肿瘤死亡率较低，但复发率较高。治疗主要以手术为主，但要尽量做到临床确诊后选择合理手术方式，并根据病理学类型决定治疗用药和术后处理，二者结合对于提高诊断率，减少复发率有一定意义。

Purpose: To provide references on clinical diagnose ＆ treatment and comprehend the clinical characters ＆ prognosi by retrospectively analyzing the 273 cases paraffin specimens from Dec. 1961 to Jun. 2002 of ophthalmic pathology room, Beijing Tongren Hospital. Materials ＆ method: Patient’s history、age、gender、eye、evaginatio、visual acuity、Ultrasound B scan、X ray、 CT、MRI、 pre- and post- operation condition、follow-up data and other clinical features are collected from 261 patients, 273 paraffin specimens. These data is sorted out with their pathological features.Results: In epithelial tumors of lacrimal gland, pleomorphic adenoma is the first common seen followed with the subsequce from high to low rate of adenoid cystic carcinoma、pleomorphic adenocarcinoma、adenocarcinoma. 12 cases recurrented more than once. The recurrence rate is 4.6%.Conclusion: Pleomorphic adenoma is the most common in epithelial tumors of lacrimal gland. The death rate is low, while the recurrence rate is relatively high. It is significant to choose the proper operation, medicine and post-surgury therapy.