目的：观察非穿透性小梁切除联合小梁切开术治疗原发性开角型青光眼的临床效果。
方法：对10例12眼原发性开角型青光眼患者行非穿透性小梁切除联合小梁切开术，术中应用丝裂霉素C，术后观察视力、前房反应、眼压、滤过泡情况，随诊时间3月。
结果：10例12眼术前眼压36.6±11.8mmhg（23.3－60.7mmhg），术后1天6.2±2.8mmhg（4.2－8.3mmhg），术后1周7.3±3.7mmhg（4.6－10.8mmhg），术后2周9.6±4.2mmhg（8.2－14mmhg），术后1月12.7±4.7mmhg（8.5－15.6mmhg），术后2月11.5±4.2mmhg（8.0－14.8mmhg），术后3月12.2±4.4mmhg（8.0－16.2mmhg）。术后视力均达到或高于术前水平。12眼均有功能型滤泡。术中、术后均未出现浅前房及前方炎症反应。例有1例术中少量前房出血，于第二天全部吸收。
结论：非穿透性小梁切除联合小梁切开术能安全、有效地治疗原发性开角型青光眼，成功率高于单纯性非穿透性小梁手术。
Objectives:To observe the clinical effect of nonperforating trabecular surgery(NPTS) combined with trabeculotomy in primary open-angle glaucoma (POAG)。Methods：12 eyes of 10 patients with POAG were performed with NPTS combined trabeculotomy and mitomycin C (MMC) during operation。The visual acuity，intraocular pressure(IOP),inflammation and filtering bled were observed after surgery。Results：The mean intraocular pressure of 12 eyes was 36.6±11.8mmhg before operation。After operation，the mean Lop was 6.2±2.8mmhg in one day (12 eyes)，7.3±3.7mmhg in one week (12eyes)，9.6±4.2mmhg in two weeks (12eyes)，12.7±4.7mmhg in one month (12 eyes)，11.5±4.2mmhg in two months(10 eyes)，12.2±4.4mmhg in therr months(9 eyes)。Visual acuity improved or remained stable in 12 eyes after operation。All of these cases had effective filtering bled。There was no flat anterior chamber, inflammation existed during and after operation。Hyphema occurred in only one eye during operation and disappeared whining one day。Conclusion：NPTS combined with trabeculotomy is a effective and safe treatment for POAG.。Compared with simple NPTS，it could improve the operative efficiemcy。
Methods：12 eyes of 10 patients with POAG were performed with NPTS combined trabeculotomy and mitomycin C (MMC) during operation。The visual acuity，intraocular pressure(IOP),inflammation and filtering bled were observed after surgery。Results：The mean intraocular pressure of 12 eyes was 36.6±11.8mmhg before operation。After operation，the mean Lop was 6.2±2.8mmhg in one day (12 eyes)，7.3±3.7mmhg in one week (12eyes)，9.6±4.2mmhg in two weeks (12eyes)，12.7±4.7mmhg in one month (12 eyes)，11.5±4.2mmhg in two months(10 eyes)，12.2±4.4mmhg in therr months(9 eyes)。Visual acuity improved or remained stable in 12 eyes after operation。All of these cases had effective filtering bled。There was no flat anterior chamber, inflammation existed during and after operation。Hyphema occurred in only one eye during operation and disappeared whining one day。Conclusion：NPTS combined with trabeculotomy is a effective and safe treatment for POAG.。Compared with simple NPTS，it could improve the operative efficiemcy。
