Fig. 3. Marked conjunctival and corneal xerosis in the 25-year-old woman whose histopathologic changes are shown in Figure 1. The entire bulbar conjunctiva is dry and thickened and almost skinlike. The dry, granular appearance of the cornea is best appreciated in the area of the light reflex. (Sommer A, Sugana T, Djunaedi E, Green R: Vitamin A-responsive panocular xerophthalmia in a healthy adult. Arch Ophthalmol 96:1630, 1978)