4]目的: Activation of dopamine receptors in eye, especially in the retina, has been shown to attenuate development of form-deprivation myopia. Activation of adenosine A2A receptors are expressed in eye and have been shown to exert profound modulation on dopaminergic activity in the brain. In this study, we investigated the possible contribution of the A2A receptors to the development of myopia using adenosine A2A receptor knockout mice.;[5]方法:The expression of adenosine A2A receptors in ocular were detected by in situ hybridization. Congenic A2AR knockouts (in C57BL/6 |