Fig. 4. Paving stone degeneration. A. The retinal pigment epithelium (RPE) ends abruptly in the area of degeneration (between arrows). Insets 1 and 2. Typical circumferential lesions of paving stone degeneration. B. Higher magnification of (A). In the area of RPE disappearance, Bruch's membrane (arrows) is intact, but the overlying retina (especially the outer layers) and the underlying choroid show degenerative changes. (A, H&E, ×69; inset 1, macroscopic; inset 2, macroscopic; B, H&E, ×101)