Fig. 40. Cystinosis. A. Myriad tiny opacities give the cornea a cloudy appearance. B. Opacities occur predominantly within the corneal epithelium. C. Multiple crystals can be seen in the retinal pigment epithelium. D. A mixture of typical birefringent, rectangular cystine crystallites and fusiform bodies can be observed near the limbus. (Courtesy of SEI Photoarchives.) (Frazier PD, Wong VG: Cystinosis. Histologic and crystallographic examination of crystals in eye tissues. Arch Ophthalmol 80:87, 1968.)