Fig. 23. Central serous chorioretinopathy with multiple retinal pigment epithelium (RPE) detachments. A. This red-free photograph demonstrates the large macular neurosensory detachment. B. Early-phase fluorescein angiogram reveals three hyperfluorescent RPE defects. C. These defects do not contribute evenly to the neurosensory detachment. Although the superior macular defect is leaking fluorescein into the subretinal space intensely, the defect near the optic nerve head along the superotemporal arcade is not leaking fluorescein and does not have an overlying neurosensory detachment. D. After treatment of the RPE detachments, the neurosensory detachment has resolved. (Courtesy of Dr. Kenneth G. Noble.)