Fig. 3. Case is a 31-year-old man with a 2-year history of insulin-dependent diabetes who on routine annual examination presented with early clinically significant diabetic macular edema in his right eye (A; Color Fig. 3). Visual acuity was 20/25 in the right eye, and it was elected to follow the patient at intervals of 3 to 4 months. Partial spontaneous resolution of the macular thickening was noted two years later (B); complete resolution of the macular thickening without recurrence was noted 4 years after initial presentation (C) with visual acuity remaining at 20/25 in his right eye. Comment: This case illustrates an example in which fluorescein angiography was not indicated as the decision was made to not institute treatment and to follow the patient clinically.