Fig. 14. A. Midperiphery of the fundus of a patient with hemoglobin SC disease. Note the proliferation of new vessels producing a “sea fan” configuration. Inferiorly there is a vitreous hemorrhage. The patient has Stage 4 disease. B. Fluorescein angiogram of A shows a tortuous artery supplying the sea fan and a retinal vein draining the structure. Prominent hyperfluorescence of the sea fan is due to dye leakage into the vitreous. Also note the marked capillary nonperfusion surrounding this vascular anomaly.