Fig. 10. Fluconazole concentrations in cornea and serum after 1, 3, or 5 days' administration of 35 mg/kg/day of drug given as a single dose every 24 hours or divided and given every 12 hours. Values represent trough levels. (Reprinted with permission from O'Day, DM, Foulds G, Williams TE et al: Ocular uptake of fluconazole following oral administration. Arch Ophthalmol 108(7):1006, 1990)