Fig. 3. Frontal view, late fifth week embryo demonstrating prominent anteriorly located nasal pits with the nonfused inferior portion connecting to the recently perforated stomodeum. (Fries PD, Katowitz JA: Congenital craniofacial anomalies of ophthalmic importance. Surv Ophthalmol 35:87, 1990, with permission from Elsevier Science.)