Fig. 2. Wound modulation and revision. A. MMC decreases the likelihood of bleb failure in high-risk eyes undergoing combined cataract and glaucoma surgery. Overusage of this potent cytotoxic drug should be avoided owing to a myriad of problems related to the formation of an avascular bleb. B. Office-based laser revision of the operative wound allows for increased postoperative flexibility with less complications. The correct number and tension of scleral flap sutures allows the surgeon to strive for a safe immediate postoperative IOP range. When fibrosis occurs at approximately 1 week, suturelysis or release of sutures increases filtration while avoiding unwanted hypotony.