Fig. 4. Superficial perimacular flecks in a 15-year-old boy with normal vision. Alport's nephritis was diagnosed at the age of 3 years and progressed to end-stage renal disease at the age of 14 years. Perceptive high-tone hearing loss was detected at the age of 11 years. The proband's mother has had persistent microscopic hematuria since the age of 20 years but had no other manifestations of the disease.