Fig. 12. A. Fluorescein angiogram of the left eye of a 40-year-old man with homozygous sickle cell anemia, demonstrating an irregular foveal avascular zone (FAZ), hairpin loops, and loss of the temporal capillary network. B. Fluorescein angiogram of the right macula of a 38-year-old woman with homozygous sickle cell anemia, showing an abnormal FAZ, hairpin loop (arrowhead), and pathologic avascular zones (arrows).