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Comparison of localized retinal nerve fiber layer defects between a superior nerve fiber layer defect group and inferior nerve fiber defect group in normal tension glaucoma patients Junglim Kim, M.D.1,2, Jungmin Lee, M.D.¹, Donghee Im, M.D.¹, Changwon Kee, M.D.¹ ¹Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea Purpose : To compare the features according to the location of retinal nerve fiber layer (RNFL) defect between superior RNFL defect and inferior RNFL defect in normal-tension glaucoma (NTG) patients. Methods : Twenty two eyes showing superior localized RNFL defect (Group A) and forty seven eyes showing inferior localized RNFL defect (Group B) and corresponding visual field defect were recruited for this study. All participants completed refraction, baseline intraocular pressure (IOP), central corneal thickness (CCT) measurement, stereoscopic disc photography, RNFL photography, automated perimetry and optical coherence tomography (OCT). Mean RNFL thickness was measured by OCT. On RNFL photography, angle of the defect to the macular and width of the defects which were measured by computer aided planometry were compared between the two groups. Results : Age, systemic disease, spherical equivalent of refraction, CCT, RNFL thickness, mean deviation (MD), and pattern standard deviation (PSD) were not different between the 2 groups. Width of the defects was significant wider in group B than in group A, whereas MD and RNFL thickness were not different between 2 groups. Conclusions : At the same level of visual field defect, inferior localized RNFL defect was wider than superior localized RNFL defect. Therefore, NTG patients with superior RNFL defect should be more carefully observed. |
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